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Dr. Sam Madeira's avatar

Not surprised since I do see this clinically, all the time, as I'm sure you do too.

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Adam Rinde's avatar

I thought you would like this one. Yeah. I see it but it is great to know the mechanism. LPS ...those little pieces of "sh..." mess so many things up..

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Dr. Sam Madeira's avatar

Down with LPS! Would be curious to see studies of the oral biome and LPS and how it causes this influencing LH adversely and the gut microbiome as well. It's an often missed aspect of the biome health and frequently overlooked by internal medicine doctors and even us NDs/NMDs.

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Adam Rinde's avatar

Good thoughts! Leaky mouth is a thing! Also oral biome seeding the GIT

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Adam Rinde's avatar

Also another thing to add here.... dysbiosis leads to elevated gut beta-glucuronidase and intestinal reuptake of estrogen that would have otherwise been eliminated through the bowels. Not a good situations. Low Testosterone and elevated Estrogens.

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